Dr. Sheth joined Astrocyte Pharmaceuticals as their Chief Medical Advisor in 2022. He is the founding Chief of the Division of Neurocritical Care & Emergency Neurology and Director of the Yale Center of Brain & Mind Health. Dr. Sheth is recognized for his leadership in prevention, acute treatment, and recovery trials of brain injury. He has led and developed highly innovative programs in drug development, translation, and medical devices. His team at Yale has served as a national model for academic critical care and stroke neurology units. Dr. Sheth has served as PI or co-PI for 8 multicenter clinical trials in stroke, as well as chair for clinical endpoint and data safety monitoring committees for several pivotal studies. He is a winner of the prestigious Robert Siekert Award from the American Heart Association (AHA), the Derek Denny Brown Award from the American Neurological Association and an elected member of the American Society for Clinical Investigation (ASCI). His research has been funded by the NIH, American Academy of Neurology, AHA, and the US Army. Dr. Sheth is the author of over 350 publications and has served on study sections for the NIH, AHA, FDA and NASA. He is an Associate Editor at Stroke and a member of the American Neurological Association Board of Directors.
Dr. Sheth has formed exciting partnerships with entrepreneurs, pharmaceutical companies, and medical device start-ups to bring forward highly innovative solutions. He has successfully applied for several patents and serves as a co-founder for several early-stage companies. These efforts have resulted in extensive knowledge of FDA pathways, development of phase I-III drug programs, and implementation of new technology into the clinical workspace. The principal themes of his efforts are towards collaboration and an improved understanding of neurological disease.